I. Work Performed in Relation to the Terms of Reference


        A. Develop Methods and Procedures

The Center has developed methods and procedures in several areas to implement its Terms of Reference. These areas include data collection, education, policy evaluation, communications, and collaboration.

Data collection:
The Center maintains an international database of opioid consumption data and makes these data available to numerous governmental and non-governmental organizations and individuals who are working to improve pain relief. The Center receives data on the medical consumption of morphine and other principal opioids for all countries that report to the International Narcotics Control Board (INCB). These data allow the Center to monitor consumption trends and progress to improve pain relief, to identify problem areas, and to educate health-care professionals and government officials from any country about their past and present use of opioids. The Center’s analysis of these data has been reported in numerous publications, monographs,2,3 and conference presentations and posters.

Education:
The Center has organized or participated in meetings and educational programs that bring together representatives from government, cancer control, palliative care, and education within several countries, including France, Costa Rica, Andean countries of Latin America, India, Italy, Luxembourg, and Slovenia. Such efforts, and continued networking of professionals representing government and medicine, will help create national infrastructures to ensure opioid availability and enhance the priority of a country's pain management and palliative care in the health system. The Center has developed presentations that explain the principles of opioid availability and how they are derived from international sources of authority, such as the international narcotics control treaties, the World Health Organization (WHO) and the INCB. These presentations can be helpful in understanding the policy framework for ensuring opioid availability. The Center has produced a number of monographs for distribution at national and international meetings to provide participants with information about opioid analgesic consumption trends and key resources (see Bibliography).

Policy Evaluation:
The Center evaluates policy at both the national and international levels. This work is based on a central principle of "balance," that government policies intended to prevent misuse and diversion of controlled substances should not interfere with their use for the relief of pain.4,5 From this central principle, the Center has developed 1) a set of evaluation criteria against which U.S. federal and state policies have been examined to identify provisions that may enhance or impede pain management,6 and 2) WHO Self-Assessment Guidelines to encourage national governments to achieve better pain management by identifying and overcoming regulatory and other barriers to opioid availability.5 The WHO Guidelines can be used to develop balanced national (including states, provinces or territories) drug control policies. This document, which was issued by WHO in 2000, is intended for those who make national drug control policy, as well as those who implement it. It may also be used by health-care professionals and their organizations to encourage cooperation with governments and to facilitate further education about ensuring the availability of pain medications. The Center has also developed a procedure to "diagnose" and "treat" barriers to pain management and opioid availability, applying a medical model to policy problems.

Communications:
The Center is improving its capacity to disseminate its work to a wide international audience through publications, conference participation, networking on the Internet, websites, and frequent email contact with collaborators.

Collaboration:
The Center is committed to a collaborative process. The Center's collaborative policy evaluation efforts have been conducted with WHO-Geneva in drafting and finalizing new WHO Guidelines for evaluating national narcotics control policy for "balance"5 in India, and with the Pan American Health Organization (PAHO) to sponsor a workshop in the Andean countries. The aim of collaboration is to establish the relationships between government and non-government organizations that are necessary to evaluate and improve policies governing opioid availability. Examples of collaborative efforts appear throughout this report.



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