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Unavailability of opioid analgesics
for relief of pain in Africa

David E. Joranson
Senior Scientist and Director
University of Wisconsin Pain & Policy Studies Group
WHO Collaborating Center for Policy and Communications in Cancer Care


The World Health Organization (WHO) has repeatedly emphasized that relief of severe pain is possible if we implement what we already know about pain and symptom management. This means making use of the drugs that we already have, in particular the opioid analgesics, such as morphine, that are essential for the relief of pain and suffering in patients with cancer and HIV/AIDS.1-3

Indeed, the WHO uses national morphine consumption statistics as a rough indicator of progress to improve cancer pain relief.3 The absence of opioid analgesics has serious consequences for people with severe pain. If the use of opioid pain relieving medicines remains as inadequate as it is today, unnecessary pain and suffering will continue.

In Africa, where there have been a few reports about the status of opioid availability,4-6 how does the consumption of morphine compare to the rest of the world? In 1999, the mean consumption of morphine for all the countries of the world was only 5.9 milligrams per capita (mg/capita). The top consumers were twelve industrialized countries that used from 20 to 75 mg/capita. The rest of the countries used less than 20 mg/capita. The mean consumption of morphine for the African region was the lowest of all the WHO regions of the world, at 0.7 mg/capita. South Africa ranked the highest at 3.4 mg/capita.

Of the five countries participating in the WHO Demonstration Project for Palliative Care, Ethiopia and Zimbabwe did not report statistics for 1999. Three countries did report statistics: Botswana, 0.1 mg/capita; Uganda, 0.008 mg/capita; and Tanzania, 0.001 mg/capita.

The barriers to improving opioid availability and patient access are many and complex; these include overly restrictive narcotics regulations, concerns about diversion, fears about the consequences of unintentional errors, and greatly exaggerated fears that patients will become addicted.

This year, the International Narcotics Control Board called on all governments and the medical profession to review national narcotics regulations and to identify impediments to patients’ access to essential pain-relieving medications. The World Health Organization has prepared a set of guidelines exactly for that task, titled “Achieving Balance in National Opioids Control Policies”7 These new guidelines are available on the internet at (http://www.medsch.wisc.edu/painpolicy/publicat/00whoabi/00whoabi.htm). They will be used during the workshop “A Community Health Approach to Palliative Care for HIV/AIDS and Cancer Patients in Africa” in Gabarone, Botswana from 9-12 July 2002, to help identify the steps that should be taken to remove undue regulatory constraints on availability and patient access to pain medications for cancer and HIV/AIDS.


Reference List

(1) World Health Organization. Cancer Pain Relief. Geneva, Switzerland: World Health Organization; 1986.
(2) World Health Organization. Cancer Pain Relief and Palliative Care (Technical Report Series 804). Geneva, Switzerland: World Health Organization; 1990.
(3) World Health Organization. Cancer Pain Relief: With a Guide to Opioid Availability. Second ed. Geneva, Switzerland: World Health Organization; 1996. (Available through http://whqlibdoc.who.int/publications/9241544821.pdf).
(4) Beck SL. A systematic evaluation of opioid availability and use in the Republic of South Africa. J Pharm Care Pain Symptom Control. 1998;6(4):5-22.
(5) Joranson DE. Availability of opioid analgesics in Africa (Editorial). J Pharm Care Pain Symptom Control. 1998;6(4):1-4.
(6) Ajayi IO, Soyannwo OA, Adebamowo CA, Amanor-Boadu SD. Availability of opioids for cancer pain in Nigeria. Nig J Surg. 2000;7(1):25-28.
(7) World Health Organization. Achieving Balance in National Opioids Control Policy: Guidelines for Assessment. Geneva, Switzerland: World Health Organization; 2000. (Available through http://www.medsch.wisc.edu/painpolicy/publicat/00whoabi/00whoabi.htm).

 

 

 

 

 

 

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